P53 Mutation Cancer Cell Lines

The id cards include cell line data such as cancer type and atcc number when available as well as some specific information on potential misidentifications changes of identity or shared origins.

P53 mutation cancer cell lines.

One strain lncap gw had a mutation in one of two alleles at position 273 arg. Cell lines with a controversial p53 status. Colorectal cancer cell lines. Hct 116 cells contain wild type p53.

The hanbook of p53 mutation in cell lines. The tp53 gene network in the post genomic era. Tcp 2020 is composed of six select cell lines derived from colon cancer. 1 karolinska institute department of oncology pathology cancer center karolinska cck stockholm.

P53 gene structure and chromosome 17p alleles were studied in the three human prostate cancer cell lines lncap du 145 and pc 3. When the introduction of mutant p53 into p53 null cells was shown to give rise to a new phenotype. A special issue of human mutation has been released. Epub 2008 may 11.

The nci 60 panel. Bladder cancer cell lines. This panel combines wild type p53 cell lines with mutant p53 cell lines that carry hotspot mutations in one of the following codons. Esophageal cancer cell lines.

Several fundamental features of wild type and mutant proteins and their modifications are reviewed as well as animal models and clinical aspects such as recommendations for patient care. P53 mutations in cell lines. The colon cancer p53 hotspot mutation cell panel atcc no. A paradigm for cell line cross contamination.

Breast cancer cell lines. Atcc now offers our reliable authenticated tumor cell lines annotated with gene mutation infor mation from the sanger institute cosmic database. Human colon cancer cell lines with varied molecular characteristics eg. Analysis of p53 mutation status in human cancer cell lines.

Knowledgebase and statistical tools for the analysis of tp53 gene mutations in human cancers. Cell lines by gene mutation tumor cell lines become more powerful tools for cancer research and drug discovery when the genetic abnormalities that drive their phenotype are known. The p53 mutations in cell lines compendium the current version includes 2 000 and 500 cell lines with mutant tp53 and wild type tp53 respectively. Ht 29 caco 2 and sw480 contain mutated p53 were used as the panels in this study to.

This special issue on tp53 propels the tp53 gene into the post genomic era. Berglind h 1 pawitan y kato s ishioka c soussi t. 175 245 248 or 273.